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Test Code RLTE4 Leukotriene E4, Random, Urine

Important Note

This test is only orderable by the laboratory.  To request this test in EPIC, please order LAB001 MAYO MISCELLANEOUS TEST.  Fill out appropriate prompts and request the Mayo test code listed above.

If you need further assistance, please contact the laboratory at 406-414-5010.

Specimen Required

Ordering Guidance

A 24-hour urine collection is the preferred specimen type. Order TLTE4 / Leukotriene E4, 24 Hour, Urine.

Specimen Required

Supplies: Sarstedt 5 mL Aliquot Tube (T914)

Container/Tube: Plastic vial

Specimen Volume: 5 mL

Collection Instructions:

1. Collect a random urine specimen. 

2. No preservative preferred.

Useful For

An aid to evaluate patients suspected of having systemic mastocytosis using random urine collections

Profile Information

Test ID Reporting Name Available Separately Always Performed
LTE4R Leukotriene E4, Random, U No Yes
CRETR Creatinine, Random, U No Yes

Method Name

LTE4R: Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

CRETR: Enzymatic Colorimetric Assay

Specimen Type


Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Frozen (preferred) 30 days
  Refrigerated  7 days
  Ambient  24 hours

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values


≤104 pg/mg creatinine



≥18 years old: 16-326 mg/dL

Reference values have not been established for patients who are younger than 18 years of age.

Day(s) Performed

Monday, Thursday

Report Available

2 to 6 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information