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HelpTest Code LAB567 Amiodarone, Serum
Additional Codes
Mayo Test Code: AMIO
Useful For
Monitoring amiodarone therapy, especially when amiodarone is coadministered with other drugs that may interact
Evaluating possible amiodarone toxicity
Assessing patient compliance
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
Serum RedSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1.5 mL
Collection Instructions:
1. Draw blood no sooner than 12 hours (trough value) after last dose or immediately before next scheduled dose.
2. Centrifuge and aliquot serum into a plastic vial within 2 hours of collection.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum Red | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 24 hours |
Reference Values
AMIODARONE
Trough Value
0.5-2.0 mcg/mL: Therapeutic concentration
>2.5 mcg/mL: Toxic concentration
DESETHYLAMIODARONE
No therapeutic range established for desethylamiodarone; activity and serum concentration are similar to parent drug.
Day(s) Performed
Monday through Friday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
80151
Report Available
2 to 5 daysReject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Method Name
Liquid Chromatography Mass Spectrometry (LC-MS/MS)
Forms
If not ordering electronically, complete, print, and send a one of the following with the specimen:
-Therapeutics Test Request (T831)
-Cardiovascular Test Request (T724)