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Test Code LAB383 Creatinine with Estimated GFR

Useful For

Creatinine:

  • Diagnosing and monitoring treatment of acute and chronic renal diseases
  • Calculation of the fractional excretion of urine analytes
  • Monitoring renal transplant recipients

Estimated Glomerular Filtration Rate (eGFR):

Serum creatinine measurement is used in estimating GFR for people with chronic kidney disease (CKD) and those with risk factors for CKD (diabetes, hypertension, cardiovascular disease, and family history of kidney disease).

Methodology

Kinetic Colorimetric (Jaffe)

Performing Laboratory

Bozeman Health Laboratory Services

Specimen Requirements

Specimen Type: Plasma or serum
Container/Tube: Light-green top (lithium heparin gel), red top, or gold top
Specimen Volume: 1 mL
Specimen Minimum Volume: 0.5 mL

Specimen Rejection: Icteric samples can produce bias.  Highly icteric samples will be rejected.

Specimen Transport Temperature

Ambient/Refrigerated

Specimen Stability

Specimen Type Temperature Time
Plasma or Serum Ambient 7 days
  Refrigerated 7 days
  Frozen 3 months

Reference Values

Male: 0.60-1.40 mg/dL

Female: 0.50-1.00 mg/dL

eGFR: ≥60 mL/minute/1.73m2

(Includes estimated glomerular filtration rate (eGFR) calculation for all patients 18 years and older)

Additional Information

  • eGFR is based on the Modification of Diet in Renal Disease (MORD) equation.
  • If patient is African American, multiply result by 1.21.
  • Calculation is only valid for patients >18 years of age.
  • Expected values are based on a body surface area of 1.73 square meters, which is an accepted average body surface area.
  • Antibiotics containing cephalosporin lead to significant falsepositive values
  • Cefoxitin causes artificially high creatinine results
  • Cyanokit (Hydroxocobalamin) may cause interference with results
  • The presence of ketone bodies can cause artificially high results

Day(s) Test Set Up

Monday through Sunday

Test Classification and CPT Coding

82565