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Test Code LAB318 Platelet Function

Important Note

Gently mix the blood at the time of draw. Do not transport specimens in the pneumatic tube system.  Specimen must be hand-delivered to Bozeman Health Laboratory Services.

Blue tubes that are not filled to the required line will not be processed, due to result integrity being affected.   

Useful For

  • Determining the cause of, or the potential for excessive bleeding
  • Evaluating the ability of platelets to adhere and aggregate
  • Monitoring the presence and effectiveness of antiplatelet medications (such as aspirin)

Methodology

Automated/Platelet Plug Formation

 

Profile Information

Test Component

Available

Separately

Always

Performed

Epinephrine/Collagen Screen No Yes
ADP/Collagen Screen No No

Testing Algorithm:
An epinephrine/collagen screen is performed. If the screen is prolonged, then an ADP/collagen screen will be performed at an additional charge.

Performing Laboratory

Bozeman Health Laboratory Services

Specimen Requirements

Specimen must arrive and be performed within 4 hours of draw.

 

Specimen Type: Whole blood
Container/Tube: Blue top (3.2% sodium citrate)

Specimen Volume: 2 Full tubes

Collection Instructions:

  1. All investigations of platelet function are strongly dependent on the correct method of blood collection.  Venipuncture should be performed using a 21 gauge or larger needle.
  2. Immediately after draw, gently invert both tubes several times to mix blood with additive. After initial mixing, avoid agitation or rotation.
  3. Discard the sample if there is a venous collapse or stoppage of blood flow during collection.  
  4. Do not centrifuge.
  5. Forward unprocessed whole blood promptly at ambient temperature only.  Do not transport specimen in pneumatic tube system. Specimen must be hand-delivered to Bozeman Health Laboratory Services.

Specimen Rejection: Hemolyzed samples will be rejected.

Specimen Transport Temperature

Ambient

Specimen Stability

Specmen Type Temperature Time
Whole Blood  (unspun) Ambient 4 hours

Reference Values

COLLAGEN/EPINEPHRINE
94-193 seconds

 

COLLAGEN/ADP
71-118 seconds

Additional Information

  • The collagen/epinephrine test is used to detect platelet dysfunction induced by intrinsic platelet defects, von Willebrand disease, or exposure to platelet inhibiting agents (such as aspirin).
  • The collagen/ADP test is used to determine if an abnormal collagen/epinephrine result may have been caused by the effect of aspirin or medications containing aspirin.

Day(s) Test Set Up

Monday through Sunday

Test Classification and CPT Coding

85576 x 2