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Test Code LAB28 Gentamicin, Peak

Useful For

Antimicrobial drug monitoring

Methodology

Enzyme Immunoassay

Performing Laboratory

Bozeman Health Laboratory Services

Specimen Requirements

Specimen Type: Plasma or serum
Container/Tube: Light-green top (lithium heparin gel), red top, or gold top
Specimen Volume: 1 mL
Specimen Minimum Volume: 0.5 mL

Collection Instructions:

1. Draw blood 30 minutes after completion of infusion of an intravenous dose.

2. Spin down within 2 hours of draw and remove plasma or serum from cells.

3. Label specimen with date and time of draw.

Specimen Rejection: Hemolyzed samples may be rejected.

 

Additional Information: Draw time is only a recommendation. Specific circumstances related to an individual patient, eg, renal function, hepatic function, concurrent medications, signs or symptoms, and/or therapeutic response may necessitate individualization of drawing schedules.

Specimen Transport Temperature

Refrigerated

Specimen Stability

Specimen Type Temperature Time
Plasma or Serum Ambient 8 hours
  Refrigerated 1 week
  Frozen 1 month

Reference Values

Peak therapeutic concentration:                    3.0-12.0 ug/mL

Toxic concentration (automatic call-back):             >12.0 ug/mL

 

Goal levels depend on the type of infection being treated. Peak targets are generally between 5.0 and 8.0 mcg/mL for less severe infections and 8.0 and 10.0 mcg/mL for severe infections. Prolonged exposure to peak levels exceeding 12.0 mcg/mL may lead to toxicity.

Day(s) Test Set Up

Monday through Sunday

Test Classification and CPT Coding

80170