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Test Code LAB1889 Cytogenetics, Oncology Chromosome Analysis

Useful For

Identifying chromosome abnormalities

Profile Information

Test Name Extended Options
Oncology Chromosome Analysis

Reflex to FISH if cytogenetics is normal

(reflex FISH panel must be marked)

Reflex to AML Prognostic Profile

when cytogenetics is intermediate risk
Other:

 

Methodology

Karyotyping by Traditional G Banding (NeoGenomics)

Performing Laboratory

Yellowstone Pathology Institute/NeoGenomics

Specimen Requirements

Specimen Type: Bone Marrow Aspirate

Container/Tube: Sodium Heparin (dark green top)*

Additional Requirements: *Must provide EDTA tube (purple top) in addition to Sodium Heparin tube when ordering AML Reflex

Specimen Volume: 2 mL

Specimen Minimum Volume: 1 mL

Collection Instructions:

  1. Invert several times to mix bone marrow.
  2. Send specimen at ambient temperature in original container.
  3. Include a YPI requisition.

Specimen Type: Bone Marrow Core

Container/Tube: RPMI

Specimen Volume: 2 cm core length

Specimen Minimum Volume: 1 cm core length

Collection Instructions: 

  1. Send RPMI specimen at ambient temperature.
  2. Include a YPI requisition.

Specimen Type: Peripheral Blood

Container/Tube: Sodium Heparin (dark green top)

Specimen Volume: 5 mL

Specimen Minimum Volume: 2 mL

Collection Instructions:

  1. Invert several times to mix blood.
  2. Send specimen at ambient temperature in original container.
  3. Include a YPI requisition.

Specimen Type: Fresh Tissue

Container/Tube: RPMI

Specimen Minimum Volume: 2 pieces of tissue 0.2 cm3

Collection Instructions: 

  1. Send RPMI specimen at ambient temperature.
  2. Include a YPI requisition.

Specimen Type: Body Fluid

Container/Tube: RPMI

Specimen Volume: Equal parts RPMI and specimen volume

Collection Instructions: 

  1. Send RPMI specimen at ambient temperature.
  2. Include a YPI requisition.

Specimen Type: Fine Needle Aspirate

Container/Tube: RPMI

Specimen Minimum Volume: 5 mL RPMI with specimen

Collection Instructions: 

  1. Send RPMI specimen at ambient temperature.
  2. Include a YPI requisition.

 

Specimen Rejection:

1.  Unlabeled specimens

2.  Specimens collected in wrong container/tube

3.  Specimens retained past viability

Forms

Specimen Transport Temperature

Ambient

Specimen Stability

Specimen Type Temperature Time
Varies Ambient

48-72 hours*

*For optimal specimen recovery, transport specimen to YPI immediately.

Day(s) Test Set Up

Monday through Friday

Test Classification and CPT Coding

88237

88262

88291

88264 (if necessary)

88280 (if necessary)

88285 (if necessary)