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Test Code LAB1882 IgA Reflex to Celiac Cascade

Useful For

Evaluating patients suspected of having celiac disease

Profile Information

Test Code Test Name Methodology

Available

Separately

Always

Performed

LAB73 Immunoglobulin A (IgA)

Immunoturbidimetric assay

Yes Yes

Testing Algorithm:

  • If the IgA result is within the age-specified normal range, then tissue transglutaminase (tTG) IgA antibody testing will be performed at an additional charge.
  • If the tTG IgA antibody result is equivocal, then endomysial IgA and deamidated gliadin IgA antibody testing will be performed at an additional charge.
  • If the IgA result is greater or equal to 5.0 mg/dL but lower than the age-specified normal range, then tTG IgA, tTG IgG, deamidated gliadin IgA, and deamidated gliadin IgG antibody testing will be performed at an additional charge.
  • If the IgA result is below the limit of detection (<5.0 mg/dL), then tTG IgG and deamidated gliadin IgG antibody testing will be performed at an additional charge.

Reflex Tests

Test Code Test Name Performing Laboratory

Available

Separately

Always Performed
LAB723 Tissue Transglutaminase (TTG) Antibody, IgA Bozeman Outpatient Services at North 19th Yes No
LAB721 Tissue Transglutaminase (TTG) Antibody, IgG Yes No
LAB871 Gliadin (Deamidated) Antibody, IgA Yes No
LAB872 Gliadin (Deamidated) Antibody, IgG Yes No
LAB774 Endomysial Antibodies,  IgA Sanford Laboratories Yes No

 

Performing Laboratory

Bozeman Health Laboratory Services/Bozeman Outpatient Services at North 19th/Sanford Laboratories

Specimen Requirements

Specimen Type: Serum
Container/Tube: Red top or Gold top

Specimen Volume: 5 mL (3 full tubes)

Specimen Minimum Volume: 2.5 mL

Collection Instructions:  Allow time for specimen to clot.  Spin down within 2 hours of collection.

Specimen Rejection: 

​1.  Grossly hemolyzed or lipemic samples will be rejected. 

2.  Repeatedly freezing and thawing samples can cause analyte deterioration. Thaw only once.

 

Specimen Transport Temperature

Ambient <8 hours/Refrigerated >8 hours

Specimen Stability

Specimen Type Temperature Time
Serum Ambient 8 hours
  Refrigerated 7 days
  Frozen 1 month

Reference Values

See individual test listings

Day(s) Test Set Up

Monday, Wednesday, Friday

Test Classification and CPT Coding

82784-IgA
83516-Deaminated gliadin IgG (if appropriate)
83516-Deaminated gliadin IgA (if appropriate)

83516-tTG IgA (if appropriate)

83516-tTG IgG (if appropriate)

86255-Endomysial antibodies (if appropriate)