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Test Code LAB14 Cytology, Urine

Useful For

Cytologic evaluation is a diagnostic aid for detection of cancer, its precursors, and inclusion bodies. It is useful for detection in asymptomatic patients, in high-risk groups, and in patients with clinically-suspected carcinomas. It is also an aid in detection of benign processes such as opportunistic infections.

Methodology

Light Microscopy

Performing Laboratory

Bozeman Health Laboratory Services

Specimen Requirements

Specimen Type: Urine

Preferred: Clean catch voided

Acceptable: Catheterized or bladder washings

Container/Tube: Screw-capped container

Specimen Minimum Volume: 10 mL

Collection Instructions:  

  1. Hydrate patient (give several glasses of water 30 minutes to 1 hour prior to collection).
  2. Collect at least 75 mL from a catheterized or voided urine (preferably not first-morning voided specimen) or bladder washings obtained at time of cystoscopy in container.
  3. Add an equal amount of 50% ethanol or reagent alcohol to fix specimen.  If no preservative is used, keep specimen refrigerated.
  4. Label container with patient’s name (first and last), date and actual time of collection, source and site of specimen, physician’s name, and hospital identification number (if applicable).
  5. Place specimen in plastic specimen bag with request form inserted into pocket separate from specimen, and, if possible, deliver specimen to Cytology Laboratory.

Forms: Cytology Test Requisition (see Forms-Requisitions in left column)

Include patient’s name (first and last), date of birth, date of collection, address, phone number, Social Security number, insurance information, physician’s name and address, source and site of specimen, pertinent clinical history.

Specimen Rejection: The following specimens will be returned to submitting physician:

  1. No request form
  2. Name on request form does not match name on specimen container
  3. Unlabeled specimen
  4. No doctor’s name given
  5. Spilled specimen

Specimen Transport Temperature

Unpreserved-Refrigerated

Preserved-Ambient

Reference Values

Diagnostic interpretation is based on morphologic cellular changes and is reported to the clinician using descriptions, comments, and recommendations when appropriate.

 

Note: Cells observed in the specimen received may not represent the true nature of the lesion or clinical conditions because of sampling fallibility. A negative cytologic diagnosis does not rule out the possibility of an existing malignancy.

Day(s) Test Set Up

Monday through Friday

Test Classification and CPT Coding

88112-Selective cellular enhancement technique with interpretation (eg, liquid based slide preparation method)

88305-Level IV-surgical pathology, gross and microscopic examination