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HelpTest Code LAB1230009 Vitamin B12, Reflex to Methylmalonic Acid (MMA)
Useful For
Investigating the presence and etiology of anemia
Profile Information
| Test Code | Test Name | Methodology |
Available Separately |
Always Performed |
|---|---|---|---|---|
| LAB67 | Vitamin B12 | Electrochemiluminescence Immunoassay (ECLIA) | Yes | Yes |
Testing Algorithm:
If Vitamin B12 is <300 pg/mL, then MMA testing will be performed, at an additional charge.
Reflex Tests
| Test Code | Test Name | Performing Laboratory |
Available Separately |
Always Performed |
|---|---|---|---|---|
| LAB835 | Methylmalonic Acid (MMA) | Mayo Medical Laboratories | Yes | No |
Performing Laboratory
Bozeman Health Laboratory Services/Mayo Medical Laboratories
Specimen Requirements
Specimen Type: Serum
Container/Tube: Red top, or gold top
Specimen Volume: 3 mL
Specimen Minimum Volume: 1 mL
Collection Instructions:
- Patient should be fasting.
- Spin down and refrigerate serum/plasma within 2 hours of collection.
Specimen Rejection:
1. Grossly hemolyzed samples will be rejected.
2. Samples with extremely high total protein concentrations will be rejected.
Additional Information
Samples with extremely high total protein concentrations are not suitable for use in this assay. Hyperproteinemia can be found in Lymphoma, bone marrow disorders such as multiple myeloma, monoclonal gammopathy of undetermined significance (MGUS), Waldenström macroglobulinemia, plasmocytoma and amyloidosis.
Specimen Transport Temperature
Refrigerated <24 hours/Frozen >24 hours
Specimen Stability
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Ambient | 2 hours |
| Refrigerated | 24 hours | |
| Frozen | 56 days |
Reference Values
Vitamin B12:
232-1245 pg/mL
Note: Results >2000 pg/mL will be reported as >2000 pg/mL.
MMA: See individual test listing
Day(s) Test Set Up
Monday through Friday
Test Classification and CPT Coding
82607
83921 (if needed)