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Test Code NBLD0297 UroVysion for Detection of Bladder Cancer, Urine

Additional Codes

Mayo Test Code: FUROC

Useful For

Monitoring for tumor recurrence in patients with a history of urothelial carcinoma involving the bladder or upper urinary tract.


Assessing patients with hematuria for urothelial carcinoma.

Special Instructions

Method Name

Fluorescence In Situ Hybridization (FISH) Using DNA Probes

Specimen Type


Specimen Required

Specimen Type: Urine (voided urine, catheterized urine, bladder washings, stoma collections, ureteral brushings or washings, and renal pelvic brushings or washings)


Preferred: FISH for Urothelial Carcinoma in Urocyte Urine Collection Kit (T509)

Acceptable: 70% ethanol, PreservCyt, CytoLyt

Specimen Volume: 30 mL

Collection Instructions:

1. Specimen source is required on request form.

2. Follow instructions included with Urocyte Urine Collection Kit.

3. If kit is not used, submit a random urine specimen with an equal volume of 70% ethanol, PreservCyt, or CytoLyt.

Additional Information: Provide fixative, source, reason for referral (Evaluate for urothelial carcinoma or Hematuria. Evaluate for urothelial carcinoma.) and status of diagnosis (known previous diagnosis or suspected/unknown).

Specimen Minimum Volume

30 mL is recommended, however, will not reject if <30 mL

Specimen Stability Information

Specimen Type Temperature Time
Varies Refrigerated (preferred)

Reject Due To









Reference Values

An interpretive report will be provided.

Day(s) and Time(s) Performed

Monday through Friday; 6 a.m.-8 p.m., Saturday 10 a.m.-6:30 p.m. and Sunday; 1 p.m.-9:30 p.m.

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information



1. Pathology/Cytology Information (T707) in Special Instructions

2. If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

Pathology Test Request Form (T246) (

Oncology Test Request Form (T729) (