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Test Code LABS0700 Oxycodone with Metabolite Confirmation, Urine

Additional Codes

Mayo Test Code: OXYCU

Useful For

Detection and quantification of oxycodone, oxymorphone, noroxycodone, and noroxymorphone in urine

Specimen Type

Urine


Specimen Required


Collection Container/Tube: Plastic urine container

Submission Container/Tube: Plastic, 60-mL urine bottle

Specimen Volume: 20 mL

Collection Instructions:

1. Collect a random urine specimen.

2. Submit 20 mL in 1 plastic bottle.

3. No preservative.

Additional Information:

1. No specimen substitutions.

2. No STATS are acceptable for this procedure.

3. For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody testing, order OXYCX / Oxycodone with Metabolite Confirmation, Chain of Custody, Urine.

4. Additional drug panels and specific requests are available. Call Mayo Medical Laboratories at 800-533-1710 or 507-266-5700.

5. If urine creatinine is required or adulteration of the sample is suspected, the following test should be requested, ADULT / Adulterant Survey, Urine. For additional information, please refer to ADULT / Adulterant Survey, Urine.


Specimen Minimum Volume

2.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  14 days

Reject Due To

Hemolysis

Mild OK; Gross OK

Lipemia

NA

Icterus

Mild OK; Gross OK

Other

NA

Reference Values

Negative

Cutoff concentrations:

Oxycodone-by LC-MS/MS: 25 ng/mL

Noroxycodone-by LC-MS/MS: 25 ng/mL

Oxymorphone-by LC-MS/MS: 25 ng/mL

Noroxymorphone-by LC-MS/MS: 25 ng/mL

Day(s) and Time(s) Performed

Monday through Friday

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

80365

G0480 (if appropriate)

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)