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Test Code BLOD0548 Acetaminophen, Plasma or Serum

Useful For

Monitoring toxicity in overdose cases


Enzymatic/Colorimetric/Bichromatic End point

Performing Laboratory

Bozeman Health Laboratory Services

Specimen Requirements

Specimen Type: Plasma or serum
Container/Tube: Light-green top (lithium heparin gel), red top, or gold top

Specimen Volume: 1 mL
Specimen Minimum Volume: 0.5 mL

Collection Instructions: Label specimen as plasma or serum.

Specimen Transport Temperature


Specimen Stability

Specimen Type Temperature Time
Plasma or Serum Ambient 14 days
  Refrigerated 14 days
  Frozen 45 days


Reference Values

Therapeutic concentration: 10-30 µg/mL
Toxic concentration (automatic call-back): >150 µg/mL


Acetaminophen concentrations >150 µg/mL at 4-hours after ingestion and >50 µg/mL at 12-hours after ingestion are often associated with toxic reactions.

Note: Therapeutic acetaminophen concentrations vary significantly depending on the individual patient. A range of 10 µg/mL to 30 µg/mL may be an effective specimen concentration for many patients; however, some individuals are best treated at concentrations outside this range. The physician must determine the appropriate therapeutic range for each patient.

Day(s) Test Set Up

Monday through Sunday

Test Classification and CPT Coding