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Test Code BLOD0541 Theophylline, Plasma or Serum

Useful For

Monitoring therapeutic drug levels. Theophylline is used as a bronchodilator for the treatment of moderate to severe asthma and chronic obstructive pulmonary disease (COPD).


Particle-Enhanced Turbidimetric Inhibition Immunoassay (PETINIA)

Performing Laboratory

Bozeman Health Laboratory Services

Specimen Requirements

Specimen Type: Plasma or Serum
Container/Tube: Light-green top (lithium heparin gel), red top tube or gold top tube
Specimen Volume: 2 mL
Specimen Minimum Volume: 1 mL

Collection Instructions:

1. Date and time of last dose and date and time of draw are required.

2. Spin down and separate cells within 2 hours of draw.  

Specimen Rejection:

1. Uncentrifuged specimens >2 hours old

Specimen Transport Temperature


Specimen Stability


Specimen Type Temperature Time
Plasma or Serum Ambient 8 hours
  Refrigerated 48 hours
  Frozen 1 month


Reference Values

Therapeutic concentration: 10.0-20.0 µg/mL

Note: Therapeutic levels are based on trough levels.


Toxic concentration (automatic call-back): >20.0 µg/mL

Day(s) Test Set Up

Monday through Sunday

Test Classification and CPT Coding