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Test Code BLOD0306 Jo-1 Antibodies, IgG

Useful For

Evaluating patients with signs and symptoms of a connective tissue disease in whom the test for antinuclear antibodies is positive.  Jo-1 antibodies can be found as markers in polymyositis/dermatomyositis and in patients with polymyositis overlap syndrome. They are associated with intestinal pneumonitis (in the context of myositis) and occur in a far smaller portion of children with myositis than adults. Patients with Jo- 1 antibodies tend to have a severe form of the disease with a tendency to relapse and poorer prognosis.

Methodology

Enzyme-linked fluorescent immunoasay (EliA)

Performing Laboratory

Bozeman Outpatient Services at North 19th

Specimen Requirements

Specimen Type: Serum
Container/Tube: Gold top
Specimen Volume: 1 mL
Specimen Minimum Volume: 0.5 mL

Specimen Rejection: 

​1.  Grossly hemolyzed or lipemic samples will be rejected. 

2.  Repeatedly freezing and thawing samples can cause analyte deterioration. Thaw only once.

Specimen Transport Temperature

Ambient <8 hours/Refrigerated <48 hours/Frozen >48 hours

Specimen Stability

 

Specimen Type Temperature Time
Serum Ambient 8 hours
  Refrigerated 48 hours
  Frozen 30 days

 

Reference Values

Negative

 

<7.0 U/mL (negative)

7.0-10.0 U/mL (equivocal)

>10.0 U/mL (positive)

Day(s) Test Set Up

Monday, Wednesday, Friday

 

Turnaround Time: Same day as performed

Test Classification and CPT Coding

86235